Effect of systemic bevacizumab therapy on retinal pigment epithelial detachment
نویسندگان
چکیده
منابع مشابه
Treatment of retinal pigment epithelial detachment with antiangiogenic therapy
PURPOSE Evaluate the efficacy of pegaptanib, a selective anti-vascular endothelial growth factor (VEGF) agent, and bevacizumab, a nonselective anti-VEGF agent, for retinal pigment epithelial detachment (PED) associated with occult choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). METHODS Prospective, comparative, nonrandomized pilot study included patient...
متن کاملRetinal pigment epithelial tears following ranibizumab therapy for fibrovascular retinal pigment epithelial detachment due to occult age-related macular degeneration
BACKGROUND The aim of this paper is to report the incidence of retinal pigment epithelial (RPE) tears in patients treated with ranibizumab for subfoveal fibrovascular retinal pigment epithelial detachment (FVPED) due to occult age-related macular degeneration (AMD). MATERIAL/METHODS Thirty patients were treated according to the following schedule: saturation phase, further treatment was based...
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We describe a case of macular hole (MH) closure after intravitreal bevacizumab therapy for an underlying pigment epithelial detachment (PED) due to exudative age-related macular degeneration (AMD). The 73-year-old Caucasian female presented with reduced visual acuity (20/80) of the left eye and metamorphopsia for approximately 6 months. Spectral domain optical coherence tomography revealed a su...
متن کاملThe onset of pigment epithelial proliferation after retinal detachment.
The adult mammalian retinal pigment epithelium (RPE) is mitotically inactive, yet retains the capacity to proliferate under certain conditions. To determine the onset of RPE proliferation after retinal detachment, we examined experimentally detached cat retinas of 12, 24, 48, and 72 hr duration. An additional animal served as a nondetached, sham-operated control. 3H-thymidine was injected into ...
متن کاملRetinal detachment in the cat: the pigment epithelial-photoreceptor interface.
Twenty-six cat retinae were surgically detached by injecting fluid into the subretinal space (SRS). The retinae were then studied by light and electron microscopy at detachment intervals ranging from 1/2 hr to 14 months. Degenerative and proliferative changes occur at the retinal pigment epithelial (RPE)-photoreceptor interface very soon after detachment, and the severity of these changes depen...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2006
ISSN: 0007-1161
DOI: 10.1136/bjo.2006.102467